Extra Cellular Matrix Strain Device

Wed, 15 Dec 2021 18:18:57 +0000

I worked with another student to design a 3D cell-matrix strain device in AutoCAD. The device characterized the local micromechanical environment of tendon cells after cyclic loading. Simulating chronic tissue overuse, this ultimately provides insight into clinically relevant mechanisms facilitating effective tendon repair. This device was driven by two actuators that gripped the tendon to securely submerge it into different physiological test solutions.

3D Microtissue System for Artificial Tendon

Thu, 01 Apr 2021 19:11:50 +0000

Within the Andarawis-Puri group, I led an independent project by engineering a platform to investigate three-dimensional (3D) tendon cell behavior using complex imaging modalities. To accomplish this project, I designed and fabricated a polydimethylsiloxane (PDMS) mold with the goal of embedding tendon cells within a collagen hydrogel. Over time, these cells will anchor to static posts that apply uniaxial tension, thereby creating an artificial tendon in a biomimetic mechanical environment.

I presented my work in the 2021 Cornell Undergraduate Board Fall Forum, with my presentation winning the award for Excellent Explanation.

research | Hsin Huei Chen

Extra Cellular Matrix Strain Device

3D Microtissue System for Artificial Tendon